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Duration: 16-24 weeks for significant fat loss, can extend longer with medical supervision Expected timeline: Week 1-4: Appetite reduction, initial weight loss beginning Week 4-12: Consistent fat loss of 1-2 pounds weekly Week 12-24: Significant body composition transformation Cost estimate: $300-600 per month depending on semaglutide source See the peptides for weight loss guide for comprehensive information

Clinical Implications for Practice For healthcare professionals managing reproductive-aged adults on GLP-1 therapy: Counsel proactively regarding possible restoration of fertility with improved metabolic health

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The study examined safety parameters and metabolic biomarkers over a 12-week treatment period [2]